Overview of Chosen Chemical Compounds and Intermediates
Overview of Chosen Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the treatment of various myeloma. Its synthesis or analyze is critical for making certain the purity and protection of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound while in the synthesis of imatinib, a drug that targets particular kinds of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their study is crucial for optimizing the creation approach and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lenvatinib Impurity b Lapatinib is employed to take CAS NO.152460-10-1 care of breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Utilized in the treatment of breast cancer. A variety of intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal most cancers and small cell lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, which have different apps, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to control blood sugar stages.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is linked to the synthesis of various gluconic acid derivatives, which might be Utilized in foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication used to control form 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).